Multiplex methylated DNA testing in plasma with high sensitivity and specificity for colorectal cancer screening

Methylated SEPT9 showed relatively low sensitivity in detecting early stage colorectal cancer (CRC) and advanced adenomas (AA) in plasma. Combination of multiple biomarkers was an effective strategy to improve sensitivity in early stage cancer diagnosis and screening. A new qPCR‐based assay combinin...

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Detalhes bibliográficos
Publicado no:Cancer Med
Main Authors: Zhao, Guodong, Li, Hui, Yang, Zixuan, Wang, Zhenzhen, Xu, Manqiu, Xiong, Shangmin, Li, Shiming, Wu, XiaoTing, Liu, Xiaoyu, Wang, Ziwen, Zhu, Yun, Ma, Yong, Fei, Sujuan, Zheng, Minxue
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Clinical Cancer Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6745865/
https://ncbi.nlm.nih.gov/pubmed/31407497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.2475
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