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Amplification and attenuation of lung metastases depending on glucocorticoid dosage implicating long‐acting activated memory cells induced by nivolumab against malignant melanoma

Firstly, glucocorticoids such as prednisolone can attenuate the effect of anti–PD‐1 antibody nivolumab. Secondly, malignant melanoma cells survived latently and unnoticeably in places other than those of previous metastatic lesions. Thirdly, effector T cells activated by nivolumab sustained their me...

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Detalhes bibliográficos
Publicado no:Clin Case Rep
Main Authors: Katagiri, Katsunori, Shiga, Kiyoto, Saito, Daisuke, Oikawa, Shin‐ichi, Ikeda, Aya, Tsuchida, Kodai, Miyaguchi, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6745446/
https://ncbi.nlm.nih.gov/pubmed/31534732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ccr3.2349
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