Association study of rs3846662 with Alzheimer’s disease in a population-based cohort: the Cache County Study

3-Hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR) is associated with monitoring cholesterol levels. The presence of the single nucleotide polymorphism rs3846662 introduces alternative splicing at exon 13; the exclusion of this exon leads to a reduction in total cholesterol levels. Lower choles...

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Pubblicato in:Neurobiol Aging
Autori principali: Wright, Sage M., Jensen, Samantha L., Cockriel, Kristen L., Davis, Brian, Tschanz, JoAnn T., Munger, Ronald G., Corcoran, Christopher D., Kauwe, John S.K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6745283/
https://ncbi.nlm.nih.gov/pubmed/30975575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2019.03.004
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