miR-221 Alleviates the Ox-LDL-Induced Macrophage Inflammatory Response via the Inhibition of DNMT3b-Mediated NCoR Promoter Methylation

Atherosclerosis (AS) is a chronic inflammatory disease, and macrophages play a key role in all phases of AS. Recent studies have shown that miR-221 is a biomarker for AS and stroke; however, the role and mechanism of miR-221 in AS are unclear. Herein, we found that miR-221 and NCoR levels were decre...

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Detalhes bibliográficos
Publicado no:Mediators Inflamm
Main Authors: Ye, Jinshan, Wu, Yaxi, Guo, Ruiwei, Zeng, Wenjun, Duan, Yanan, Yang, Zhihua, Yang, Lixia
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6745124/
https://ncbi.nlm.nih.gov/pubmed/31565033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/4530534
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