6-Phosphofructo-2-kinase/fructose-2,6-biphosphatase-2 regulates TP53-dependent paclitaxel sensitivity in ovarian and breast cancers

PURPOSE: Paclitaxel is an integral component of primary therapy for breast and epithelial ovarian cancers, but less than half of these cancers respond to the drug. Enhancing the response to primary therapy with paclitaxel could improve outcomes for women with both diseases. EXPERIMENTAL DESIGN: Twel...

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Detaylı Bibliyografya
Yayımlandı:Clin Cancer Res
Asıl Yazarlar: Yang, Hailing, Zhang, Shu, Jiang, Yongying, Mao, Weiqun, Pang, Lan, Redwood, Abena, Jeter-Jones, Sabrina, Jennings, Nicholas, Ornelas, Argentina, Zhou, Jinhua, Rodriguez-Aguayo, Cristian, Bartholomeusz, Geoffrey, Iles, LaKesla R., Zacharias, Niki M., Millward, Steven W., Lopez-Berestein, Gabriel, Le, Xiao-Feng, Ahmed, Ahmed A., Piwnica-Worms, Helen, Sood, Anil K., Bast, Robert C., Lu, Zhen
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744996/
https://ncbi.nlm.nih.gov/pubmed/31391192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-3448
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