Radiosensitization by Histone H3 Demethylase Inhibition in Diffuse Intrinsic Pontine Glioma

PURPOSE: Radiation therapy (RT) has long been and remains the only treatment option for diffuse intrinsic pontine glioma (DIPG). However, all patients show evidence of disease progression within months of completing radiation therapy. No further clinical benefit has been achieved using alternative r...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Katagi, Hiroaki, Louis, Nundia, Unruh, Dusten, Sasaki, Takahiro, He, Xingyao, Zhang, Ali, Ma, Quanhong, Piunti, Andrea, Shimazu, Yosuke, Lamano, Jonathan Balquiedra, Carcaboso, Angel M., Tian, Xiao, Seluanov, Andrei, Gorbunova, Vera, Laurie, Kathryn L, Kondo, Akihide, Wadhwani, Nitin R, Lulla, Rishi, Goldman, Stewart, Venneti, Sriram, Becher, Oren Josh, Zou, Lihua, Shilatifard, Ali, Hashizume, Rintaro
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744979/
https://ncbi.nlm.nih.gov/pubmed/31227500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-3890
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