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Therapeutic genome editing of triple-negative breast tumors using a noncationic and deformable nanolipogel

Triple-negative breast cancer (TNBC), which has the highest mortality rate of all breast cancer, is in urgent need of a therapeutic that hinders the spread and growth of cancer cells. CRISPR genome editing holds the promise of a potential cure for many genetic diseases, including TNBC; however, its...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Guo, Peng, Yang, Jiang, Huang, Jing, Auguste, Debra T., Moses, Marsha A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744870/
https://ncbi.nlm.nih.gov/pubmed/31451668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1904697116
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