Strategies for the expansion of human induced pluripotent stem cells as aggregates in single-use Vertical-Wheel™ bioreactors

BACKGROUND: Since their inception, human induced pluripotent stem cells (hiPSCs) have held much promise for pharmacological applications and cell-based therapies. However, their potential can only be realised if large numbers of cells can be produced reproducibly on-demand. While bioreactors are ide...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Eng
Hauptverfasser: Nogueira, Diogo E. S., Rodrigues, Carlos A. V., Carvalho, Marta S., Miranda, Cláudia C., Hashimura, Yas, Jung, Sunghoon, Lee, Brian, Cabral, Joaquim M. S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744632/
https://ncbi.nlm.nih.gov/pubmed/31534477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13036-019-0204-1
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