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CD69 Targeting Enhances Anti-vaccinia Virus Immunity

CD69 is highly expressed on the leukocyte surface upon viral infection, and its regulatory role in the vaccinia virus (VACV) immune response has been recently demonstrated using CD69(−/−) mice. Here, we show augmented control of VACV infection using the anti-human CD69 monoclonal antibody (MAb) 2.8...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Notario, Laura, Redondo-Antón, Jennifer, Alari-Pahissa, Elisenda, Albentosa, Almudena, Leiva, Magdalena, Lopez, Daniel, Sabio, Guadalupe, Lauzurica, Pilar
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744249/
https://ncbi.nlm.nih.gov/pubmed/31315995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00553-19
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