Single-Dose Vaccination with a Hepatotropic Adeno-associated Virus Efficiently Localizes T Cell Immunity in the Liver with the Potential To Confer Rapid Protection against Hepatitis C Virus

Hepatitis C virus (HCV) is a significant contributor to the global disease burden, and development of an effective vaccine is required to eliminate HCV infections worldwide. CD4(+) and CD8(+) T cell immunity correlates with viral clearance in primary HCV infection, and intrahepatic CD8(+) tissue-res...

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Bibliografische gegevens
Gepubliceerd in:J Virol
Hoofdauteurs: Mekonnen, Zelalem A., Grubor-Bauk, Branka, English, Kieran, Leung, Preston, Masavuli, Makutiro G., Shrestha, Ashish C., Bertolino, Patrick, Bowen, David G., Lloyd, Andrew R., Gowans, Eric J., Wijesundara, Danushka K.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2019
Onderwerpen:
Vaccines and Antiviral Agents
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744243/
https://ncbi.nlm.nih.gov/pubmed/31292249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00202-19
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