Complement-Mediated Neutralization of a Potent Neurotropic Human Pathogen, Chandipura Virus, Is Dependent on C1q

Among the innate immune sentinels, the complement system is a formidable first line of defense against pathogens, including viruses. Chandipura virus (CHPV), a neurotropic vesiculovirus of the family Rhabdoviridae, is a deadly human pathogen known to cause fatal encephalitis, especially among childr...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Kunnakkadan, Umerali, Nag, Joydeep, Kumar, Nisha Asok, Mukesh, Reshma Koolaparambil, Suma, Sreenath Muraleedharan, Johnson, John Bernet
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744236/
https://ncbi.nlm.nih.gov/pubmed/31315998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00994-19
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