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组织蛋白酶B通过TLR4非依赖途径调控小鼠肝脏Kupffer细胞内炎症的激活
OBJECTIVE: To investigate the role of cathepsin B in hepatic Kupffer cells (KCs) in activating Toll-like receptor 4(TLR- 4)-independent inflammatory pathways in mice with lipopolysaccharide (LPS)-induced sepsis. METHODS: Eighteen wild-type (WT) mice and 18 TLR4-knockout (TLR4(-/-)) mice were both di...
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| Gepubliceerd in: | Nan Fang Yi Ke Da Xue Xue Bao |
|---|---|
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
南方医科大学学报编辑部
2018
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6744205/ https://ncbi.nlm.nih.gov/pubmed/30613015 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12122/j.issn.1673-4254.2018.12.11 |
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