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咪唑并杂环化合物的设计、合成及抗乳腺癌活性评价

OBJECTIVE: To synthesize compounds based on imidazo-fused heterocycles and evaluate their anti-tumor activity against breast cancer. METHODS: The compounds 1a-1e, 2a and 2b were synthesized by aerobic copper-catalyzed halocyclization of methyl N-heteroaromatics with aliphatic amines; 3a and 3b were...

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Detalhes bibliográficos
Publicado no:Nan Fang Yi Ke Da Xue Xue Bao
Formato: Artigo
Idioma:Inglês
Publicado em: 南方医科大学学报编辑部 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744180/
https://ncbi.nlm.nih.gov/pubmed/30377112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12122/j.issn.1673-4254.2018.09.05
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