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阻断乳腺癌细胞PD-L1减弱对共培养树突状细胞成熟的抑制作用

OBJECTIVE: To study if programmed death- ligand 1 (PL- L1) expression in breast cancer cell activates PD- L1/PD- 1 pathway in dendritic cells to inhibit dendritic cell maturation. METHODS: Human monocytes were induced to differentiate into immature dendritic cells using GM-CSF and IL-4, and further...

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Publicat a:Nan Fang Yi Ke Da Xue Xue Bao
Format: Artigo
Idioma:Inglês
Publicat: 南方医科大学学报编辑部 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6743907/
https://ncbi.nlm.nih.gov/pubmed/29891452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3969/j.issn.1673-4254.2018.05.09
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