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抑制CaMKⅡ减轻线粒体氧化应激可改善离体心脏缺血再灌注损伤
OBJECTIVE: To investigate the role of calcium/calmodulin-dependent protein kinase Ⅱ (CaMKⅡ) in myocardial ischemia-reperfusion (IR) injury in isolated perfused rat heart and explore the underlying mechanisms. METHODS: An ischemiareperfusion (IR) model was prepared using isolated rat hearts perfused...
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| Publié dans: | Nan Fang Yi Ke Da Xue Xue Bao |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
南方医科大学学报编辑部
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6743873/ https://ncbi.nlm.nih.gov/pubmed/29502057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3969/j.issn.1673-4254.2018.02.10 |
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