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苯并[a]芘暴露大鼠的皮层代谢组学研究

OBJECTIVE: To analyze the changes in endogenous small molecule metabolites after benzo[a]pyrene (B[a]P) exposure in rat cerebral cortex and explore the mechanism of B[a]P neurotoxicity. METHODS: Five-day-old SD rats were subjected to gavage administration of 2 mg/kg B[a]P for 7 consecutive weeks. Af...

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Publié dans:Nan Fang Yi Ke Da Xue Xue Bao
Format: Artigo
Langue:Inglês
Publié: 南方医科大学学报编辑部 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6743872/
https://ncbi.nlm.nih.gov/pubmed/29502054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3969/j.issn.1673-4254.2018.02.07
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