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PCR-free whole exome sequencing: Cost-effective and efficient in detecting rare mutations
In this study, we describe the development of a PCR-free whole exome sequencing method. Using this method, 2 μg DNA was sufficient for library preparation for whole exome sequencing. Furthermore, the method is simple and makes use of a commercial kit, with additional step of concentrating the captur...
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| Publicado no: | PLoS One |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6743761/ https://ncbi.nlm.nih.gov/pubmed/31518370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0222562 |
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