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Adenosine interaction with adenosine receptor A2a promotes gastric cancer metastasis by enhancing PI3K–AKT–mTOR signaling

The accumulation of adenosine in the tumor microenvironment is associated with tumor progression in many cancers. However, whether adenosine is involved in gastric cancer (GC) metastasis and progression, and the underlying molecular mechanism, is largely unclear. In this study, we find that GC tissu...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Shi, Linsen, Wu, Zhaoying, Miao, Ji, Du, Shangce, Ai, Shichao, Xu, En, Feng, Min, Song, Jun, Guan, Wenxian
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6743355/
https://ncbi.nlm.nih.gov/pubmed/31339445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E19-03-0136
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