Induction of Myeloid-Derived Suppressor Cells in Cryopyrin-Associated Periodic Syndromes

Cryopyrin-associated periodic syndromes (CAPS) are caused by mutations in the NLRP3 gene leading to overproduction of IL-1β and other NLRP3 inflammasome products. Myeloid-derived suppressor cells (MDSCs) represent a novel innate immune cell subset capable of suppressing T-cell responses. As inflamma...

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Udgivet i:J Innate Immun
Main Authors: Ballbach, Marlene, Hall, Tobias, Brand, Alina, Neri, Davide, Singh, Anurag, Schaefer, Iris, Herrmann, Eva, Hansmann, Sandra, Handgretinger, Rupert, Kuemmerle-Deschner, Jasmin, Hartl, Dominik, Rieber, Nikolaus
Format: Artigo
Sprog:Inglês
Udgivet: S. Karger AG 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6743338/
https://ncbi.nlm.nih.gov/pubmed/27351923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000446615
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