Nrf2 Negatively Regulates Type I Interferon Responses and Increases Susceptibility to Herpes Genital Infection in Mice

Herpes simplex virus-2 (HSV-2) is a leading cause of sexually transmitted infections for which no effective vaccines or prophylactic treatment currently exist. Nuclear factor erythroid 2-related factor 2 (Nrf2) is a transcription factor involved in the detoxification of reactive oxygen species (ROS)...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Gunderstofte, Camilla, Iversen, Marie Beck, Peri, Suraj, Thielke, Anne, Balachandran, Siddharth, Holm, Christian Kanstrup, Olagnier, David
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6742979/
https://ncbi.nlm.nih.gov/pubmed/31555293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02101
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