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Oligomerization of Hsp70: Current Perspectives on Regulation and Function

The Hsp70 molecular chaperone in conjunction with Hsp90 and a suite of helper co-chaperones are required for the folding and subsequent refolding of a large proportion of the proteome. These proteins are critical for cell viability and play major roles in diseases of proteostasis which include neuro...

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Publicat a:Front Mol Biosci
Autors principals: Takakuwa, Jade E., Nitika, Knighton, Laura E., Truman, Andrew W.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6742908/
https://ncbi.nlm.nih.gov/pubmed/31555664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2019.00081
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