Amino Acid-Derived Sensors For Specific Zn(2+) Detection Using Hyperpolarized (13)C Magnetic Resonance Spectroscopy

Alterations in Zn(2+) concentration are seen in normal tissues and in disease states, and for this reason imaging of Zn(2+) is an area of active investigation. Herein, enriched [1-(13)C]cysteine and [1-(13)C(2)]iminodiacetic acid were developed as Zn(2+)-specific imaging probes using hyperpolarized...

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Bibliographic Details
Published in:Chemistry
Main Authors: Wang, Sinan, Korenchan, David E., Perez, Paola M., Taglang, Céline, Hayes, Thomas R., Sriram, Renuka, Bok, Robert, Hong, Andrew S., Wu, Yunkou, Li, Henry, Wang, Zhen, Kurhanewicz, John, Wilson, David M., Flavell, Robert R.
Format: Artigo
Language:Inglês
Published: 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6742520/
https://ncbi.nlm.nih.gov/pubmed/31338914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201902771
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