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Amino Acid-Derived Sensors For Specific Zn(2+) Detection Using Hyperpolarized (13)C Magnetic Resonance Spectroscopy

Alterations in Zn(2+) concentration are seen in normal tissues and in disease states, and for this reason imaging of Zn(2+) is an area of active investigation. Herein, enriched [1-(13)C]cysteine and [1-(13)C(2)]iminodiacetic acid were developed as Zn(2+)-specific imaging probes using hyperpolarized...

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Detalhes bibliográficos
Publicado no:Chemistry
Main Authors: Wang, Sinan, Korenchan, David E., Perez, Paola M., Taglang, Céline, Hayes, Thomas R., Sriram, Renuka, Bok, Robert, Hong, Andrew S., Wu, Yunkou, Li, Henry, Wang, Zhen, Kurhanewicz, John, Wilson, David M., Flavell, Robert R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6742520/
https://ncbi.nlm.nih.gov/pubmed/31338914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201902771
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