uORF-Tools—Workflow for the determination of translation-regulatory upstream open reading frames

Ribosome profiling (ribo-seq) provides a means to analyze active translation by determining ribosome occupancy in a transcriptome-wide manner. The vast majority of ribosome protected fragments (RPFs) resides within the protein-coding sequence of mRNAs. However, commonly reads are also found within t...

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Bibliographic Details
Published in:PLoS One
Main Authors: Scholz, Anica, Eggenhofer, Florian, Gelhausen, Rick, Grüning, Björn, Zarnack, Kathi, Brüne, Bernhard, Backofen, Rolf, Schmid, Tobias
Format: Artigo
Language:Inglês
Published: Public Library of Science 2019
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6742470/
https://ncbi.nlm.nih.gov/pubmed/31513641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0222459
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