Dark-matter matters: Discriminating subtle blood cancers using the darkest DNA

The confluence of deep sequencing and powerful machine learning is providing an unprecedented peek at the darkest of the dark genomic matter, the non-coding genomic regions lacking any functional annotation. While deep sequencing uncovers rare tumor variants, the heterogeneity of the disease confoun...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Parida, Laxmi, Haferlach, Claudia, Rhrissorrakrai, Kahn, Utro, Filippo, Levovitz, Chaya, Kern, Wolfgang, Nadarajah, Niroshan, Twardziok, Sven, Hutter, Stephan, Meggendorfer, Manja, Walter, Wencke, Baer, Constance, Haferlach, Torsten
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6742441/
https://ncbi.nlm.nih.gov/pubmed/31469830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007332
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