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Development of highly efficient protocols for extraction and amplification of cytomegalovirus DNA from dried blood spots for detection and genotyping of polymorphic immunomodulatory genes

Congenital cytomegalovirus (CMV) infection is a major cause of birth defects ranging from developmental disorders to stillbirth. Most newborns affected by CMV do not present with symptoms at birth but are at risk of sequelae at later stages of their childhood. Stored dried blood spots (DBS) taken at...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Berg, Christian, Friis, Martin B., Rosenkilde, Mette M., Benfield, Thomas, Nielsen, Lene, Lüttichau, Hans R., Sundelin, Thomas
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6742235/
https://ncbi.nlm.nih.gov/pubmed/31513621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0222053
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