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Gradient Steepness Influences the Pathfinding Decisions of Neuronal Growth Cones In Vivo

Gradients of chemotropic molecules are generally thought to be fundamental for the guidance of neuronal growth cones in the developing embryo. Here we show that the grasshopper-secreted semaphorin Sema 2a is expressed in a gradient during the period of tibial Ti1 pioneer axon pathfinding into the CN...

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Pubblicato in:J Neurosci
Autori principali: Isbister, Carolyn M., Mackenzie, Paul J., To, Kenneth C. W., O'Connor, Timothy P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6742127/
https://ncbi.nlm.nih.gov/pubmed/12514216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-01-00193.2003
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