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Gonadal Hormones Affect Spine Synaptic Density in the CA1 Hippocampal Subfield of Male Rats

The effects of androgen on the density of spine synapses on pyramidal neurons in the CA1 area of the hippocampus were studied in male rats. Gonadectomy (GDNX) had no significant effect on the number of CA1 pyramidal cells but reduced CA1 spine synapse density by almost 50% (to 0.468 ± 0.018 spine sy...

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Pubblicato in:J Neurosci
Autori principali: Leranth, Csaba, Petnehazy, Ors, MacLusky, Neil J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741990/
https://ncbi.nlm.nih.gov/pubmed/12629162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-05-01588.2003
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