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Excitatory Actions of Endogenously Released GABA Contribute to Initiation of Ictal Epileptiform Activity in the Developing Hippocampus

In the developing rat hippocampus, ictal epileptiform activity can be elicited easily in vitro during the first three postnatal weeks. Changes in neuronal ion transport during this time cause the effects of GABA(A) receptor (GABA(A)-R) activation to shift gradually from strongly depolarizing to hype...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Dzhala, Volodymyr I., Staley, Kevin J.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2003
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741948/
https://ncbi.nlm.nih.gov/pubmed/12629188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-05-01840.2003
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