Time-Dependent Increases in Brain-Derived Neurotrophic Factor Protein Levels within the Mesolimbic Dopamine System after Withdrawal from Cocaine: Implications for Incubation of Cocaine Craving

Using a rat model of drug craving, we found that the responsiveness to cocaine cues progressively increases or incubates over the first 60 d of cocaine withdrawal. Here we studied whether alterations in brain-derived neurotrophic factor (BDNF) protein levels within the mesolimbic dopamine system are...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Grimm, Jeffrey W., Lu, Lin, Hayashi, Teruo, Hope, Bruce T., Su, Tsung-Ping, Shaham, Yavin
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2003
Subjects:
Brief Communication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741929/
https://ncbi.nlm.nih.gov/pubmed/12574402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-03-00742.2003
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