Accelerated Hippocampal Spreading Depression and Enhanced Locomotory Activity in Mice with Astrocyte-Directed Inactivation of Connexin43

Using a human glial fibrillary acidic protein (hGFAP) promoter-driven cre transgene, we have achieved efficient inactivation of a floxed connexin43(Cx43) gene in astrocytes of adult mice. The loss of Cx43 expression was monitored in a cell-autonomous manner via conditional replacement of the Cx43-co...

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Publicado no:J Neurosci
Main Authors: Theis, Martin, Jauch, Regina, Zhuo, Lang, Speidel, Dina, Wallraff, Anke, Döring, Britta, Frisch, Christian, Söhl, Goran, Teubner, Barbara, Euwens, Carsten, Huston, Joseph, Steinhäuser, Christian, Messing, Albee, Heinemann, Uwe, Willecke, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2003
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741919/
https://ncbi.nlm.nih.gov/pubmed/12574405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-03-00766.2003
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