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Glial Cell Line-Derived Neurotrophic Factor Alters Axon Schwann Cell Units and Promotes Myelination in Unmyelinated Nerve Fibers

Glial cell line-derived neurotrophic factor (GDNF) plays an important role in the development and maintenance of a subset of dorsal root ganglion sensory neurons. We administered high-dose exogenous recombinant human GDNF (rhGDNF) daily to adult rats to examine its effect on unmyelinated axon–Schwan...

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Pubblicato in:J Neurosci
Autori principali: Höke, Ahmet, Ho, Tony, Crawford, Thomas O., LeBel, Carl, Hilt, Dana, Griffin, John W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741898/
https://ncbi.nlm.nih.gov/pubmed/12533616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-02-00561.2003
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