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Dihydroetorphine: A Potent Analgesic: Pharmacology, Toxicology, Pharmacokinetics, and Clinical Effects

Dihydroetorphine (DHE) is one of the strongest analgesic opioid alkaloids known; it is 1000 to 12,000 times more potent than morphine. Several in vitro and in vivo studies have shown that DHE is a selective μ‐opioid receptor (OP(3)) agonist that also binds and activates all human recombinant μ‐, δ‐,...

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Detalhes bibliográficos
Publicado no:CNS Drug Rev
Main Authors: Ohmori, Satoshi, Morimoto, Yasunori
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741694/
https://ncbi.nlm.nih.gov/pubmed/12481194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1527-3458.2002.tb00236.x
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