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RX 821002 as a Tool for Physiological Investigation of α(2)‐Adrenoceptors

RX 821002 is the 2‐methoxy congener of idazoxan. In binding and tissue studies it behaves as a selective antagonist of α(2)‐adrenoceptors, with at least 5 times greater affinity for these receptors than any other binding site. It does not select between the different types of α(2)‐receptor. Although...

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Publicat a:CNS Drug Rev
Autors principals: Clarke, R. W., Harris, J.
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741674/
https://ncbi.nlm.nih.gov/pubmed/12177687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1527-3458.2002.tb00222.x
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