TLR7 Contributes to the Rapid Progression but Not to the Overall Fatal Outcome of Secondary Pneumococcal Disease following Influenza A Virus Infection

Increased risk for bacterial superinfections substantially contributes to the mortality caused by influenza A virus (IAV) epidemics. While the mechanistic basis for this lethal synergism is still insufficiently understood, immune modulation through the viral infection has been shown to be involved....

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Bibliographische Detailangaben
Veröffentlicht in:J Innate Immun
Hauptverfasser: Stegemann-Koniszewski, Sabine, Gereke, Marcus, Orrskog, Sofia, Lienenklaus, Stefan, Pasche, Bastian, Bader, Sophie R., Gruber, Achim D., Akira, Shizuo, Weiss, Siegfried, Henriques-Normark, Birgitta, Bruder, Dunja, Gunzer, Matthias
Format: Artigo
Sprache:Inglês
Veröffentlicht: S. Karger AG 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741512/
https://ncbi.nlm.nih.gov/pubmed/23154432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000345112
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