High Threshold for Induction of the Stress Response in Motor Neurons Is Associated with Failure to Activate HSF1

Heat shock protein 70 (Hsp70) protects cultured motor neurons from the toxic effects of mutations in Cu/Zn-superoxide dismutase (SOD-1), which is responsible for a familial form of the disease, amyotrophic lateral sclerosis (ALS). Here, the endogenous heat shock response of motor neurons was investi...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Batulan, Zarah, Shinder, Gayle A., Minotti, Sandra, He, Bei Ping, Doroudchi, Mohammad M., Nalbantoglu, Josephine, Strong, Michael J., Durham, Heather D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2003
Schlagworte:
Cellular/Molecular
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741252/
https://ncbi.nlm.nih.gov/pubmed/12843283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-13-05789.2003
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