Glial Reactivity in Ciliary Neurotrophic Factor-Deficient Mice after Optic Nerve Lesion

There is evidence that ciliary neurotrophic factor (CNTF), in addition to its neurotrophic activity, positively regulates astrogliosis after CNS injury. CNTF and its receptor, CNTFRα, are strongly upregulated in activated astrocytes. Application of CNTF upregulates GFAP expression in cultured astroc...

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Bibliographische Detailangaben
Veröffentlicht in:J Neurosci
Hauptverfasser: Martin, Aliki, Hofmann, Hans-Dieter, Kirsch, Matthias
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2003
Schlagworte:
Development/Plasticity/Repair
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741243/
https://ncbi.nlm.nih.gov/pubmed/12843240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-13-05416.2003
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