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The Identification and Characterization of Oxidized RNAs in Alzheimer's Disease

It has been shown that cytoplasmic RNA oxidation occurs to a great extent in the brains of Alzheimer's disease (AD) patients. The goal of this study was to isolate and identify oxidized RNA species in AD. We show that significant amounts of poly(A)(+) mRNAs are oxidized in AD brains. RNA oxidat...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Shan, Xiu, Tashiro, Hirofumi, Lin, Chien-liang Glenn
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741200/
https://ncbi.nlm.nih.gov/pubmed/12832513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-12-04913.2003
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