Exploitation of Astrocytes by Glioma Cells to Facilitate Invasiveness: A Mechanism Involving Matrix Metalloproteinase-2 and the Urokinase-Type Plasminogen Activator–Plasmin Cascade

The presence of reactive astrocytes around glioma cells in the CNS suggests the possibility that these two cell types could be interacting. We addressed whether glioma cells use the astrocyte environment to modulate matrix metalloproteinase-2 (MMP-2), a proteolytic enzyme implicated in the invasiven...

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Vydáno v:J Neurosci
Hlavní autoři: Le, Duc M., Besson, Arnaud, Fogg, Darrin K., Choi, Kyu-Sil, Waisman, David M., Goodyer, Cynthia G., Rewcastle, Barry, Yong, V. Wee
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2003
Témata:
Cellular/Molecular
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741112/
https://ncbi.nlm.nih.gov/pubmed/12764090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-10-04034.2003
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