Lighting up the Senses: FM1-43 Loading of Sensory Cells through Nonselective Ion Channels

We describe a novel mechanism for vital fluorescent dye entry into sensory cells and neurons: permeation through ion channels. In addition to the slow conventional uptake of styryl dyes by endocytosis, small styryl dyes such as FM1-43 rapidly and specifically label hair cells in the inner ear by ent...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Meyers, Jason R., MacDonald, Richard B., Duggan, Anne, Lenzi, David, Standaert, David G., Corwin, Jeffrey T., Corey, David P.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2003
Assuntos:
Cellular/Molecular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741082/
https://ncbi.nlm.nih.gov/pubmed/12764092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-10-04054.2003
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