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Multiple Molecular Determinants for Allosteric Modulation of Alternatively Spliced AMPA Receptors
Positive allosteric regulation of glutamate AMPA receptors involves conformational changes that can attenuate receptor desensitization and enhance ion flux through the channel pore. Many allosteric modulators (e.g., cyclothiazide and aniracetam) preferentially affect the flip (i) or flop (o) alterna...
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| 出版年: | J Neurosci |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Society for Neuroscience
2003
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6740967/ https://ncbi.nlm.nih.gov/pubmed/14645491 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-34-10953.2003 |
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