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Multiple Molecular Determinants for Allosteric Modulation of Alternatively Spliced AMPA Receptors

Positive allosteric regulation of glutamate AMPA receptors involves conformational changes that can attenuate receptor desensitization and enhance ion flux through the channel pore. Many allosteric modulators (e.g., cyclothiazide and aniracetam) preferentially affect the flip (i) or flop (o) alterna...

詳細記述

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書誌詳細
出版年:J Neurosci
主要な著者: Quirk, Jennifer C., Nisenbaum, Eric S.
フォーマット: Artigo
言語:Inglês
出版事項: Society for Neuroscience 2003
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6740967/
https://ncbi.nlm.nih.gov/pubmed/14645491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-34-10953.2003
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