Neuronal Migration Depends on Intact Peroxisomal Function in Brain and in Extraneuronal Tissues

Functional peroxisome deficiency, as encountered in Zellweger syndrome, causes a specific impairment of neuronal migration. Although the molecular mechanisms underlying the neuronal migration defect are at present unknown, the excess of very long chain fatty acids in brain, a consequence of peroxiso...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Janssen, Anneleen, Gressens, Pierre, Grabenbauer, Markus, Baumgart, Eveline, Schad, Arno, Vanhorebeek, Ilse, Brouwers, Annelies, Declercq, Peter E., Fahimi, Dariush, Evrard, Philippe, Schoonjans, Luc, Collen, Désiré, Carmeliet, Peter, Mannaerts, Guy, Van Veldhoven, Paul, Baes, Myriam
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2003
Schlagworte:
Development/Plasticity/Repair
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6740889/
https://ncbi.nlm.nih.gov/pubmed/14586000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-30-09732.2003
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