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Discrete Gene Loci Regulate Neurodegeneration, Lymphocyte Infiltration, and Major Histocompatibility Complex Class II Expression in the CNS

Neurodegeneration and inflammation are fundamental aspects of many neurological diseases. A genome-wide scan of the response to ventral root avulsion (VRA) in a rat F2 cross discloses specific gene regions that regulate these processes. Two gene loci displayed linkage to neurodegeneration and T cell...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Lidman, Olle, Swanberg, Maria, Horvath, Linn, Broman, Karl W., Olsson, Tomas, Piehl, Fredrik
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6740878/
https://ncbi.nlm.nih.gov/pubmed/14586010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-30-09817.2003
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