TrkB Receptor Signaling Regulates Developmental Death Dynamics, But Not Final Number, of Retinal Ganglion Cells

We investigated the effects of endogenous neurotrophin signaling on the death-survival of immature retinal ganglion cells (RGCs) in vivo. Null mutation of brain-derived neurotrophic factor [(BDNF) alone or in combination with neurotrophin 4 (NT4)] increases the peak rate of developmental RGC death a...

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Vydáno v:J Neurosci
Hlavní autoři: Pollock, Graeme S., Robichon, Regine, Boyd, Kristina A., Kerkel, Kristi A., Kramer, Melissa, Lyles, Johnalyn, Ambalavanar, Ranjini, Khan, Asema, Kaplan, David R., Williams, Robert W., Frost, Douglas O.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2003
Témata:
Development/Plasticity/Repair
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6740848/
https://ncbi.nlm.nih.gov/pubmed/14602830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-31-10137.2003
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