Elevation of Basal Intracellular Calcium as a Central Element in the Activation of Brain Macrophages (Microglia): Suppression of Receptor-Evoked Calcium Signaling and Control of Release Function

Microglia–brain macrophages are immune-competent cells of the CNS and respond to pathologic events. Using bacterial lipopolysaccharide (LPS) as a tool to activate cultured mouse microglia, we studied alterations in the intracellular calcium concentration ([Ca (2+)](i)) and in the receptor-evoked gen...

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Foilsithe in:J Neurosci
Main Authors: Hoffmann, Anja, Kann, Oliver, Ohlemeyer, Carsten, Hanisch, Uwe-Karsten, Kettenmann, Helmut
Formáid: Artigo
Teanga:Inglês
Foilsithe: Society for Neuroscience 2003
Ábhair:
Cellular/Molecular
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6740788/
https://ncbi.nlm.nih.gov/pubmed/12805281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-11-04410.2003
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