Methylprednisolone Increases Neuronal Apoptosis during Autoimmune CNS Inflammation by Inhibition of an Endogenous Neuroprotective Pathway

Optic neuritis is one of the most common clinical manifestations of multiple sclerosis (MS), a chronic inflammatory disease of the CNS. High-dosage methylprednisolone treatment has been established as the standard therapy of acute inflammation of the optic nerve (ON). The rationale for corticosteroi...

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Pubblicato in:J Neurosci
Autori principali: Diem, Ricarda, Hobom, Muriel, Maier, Katharina, Weissert, Robert, Storch, Maria K., Meyer, Roman, Bähr, Mathias
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2003
Soggetti:
Cellular/Molecular
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6740669/
https://ncbi.nlm.nih.gov/pubmed/12904460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-18-06993.2003
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