Ca(v)1.4α1 Subunits Can Form Slowly Inactivating Dihydropyridine-Sensitive L-Type Ca(2+) Channels Lacking Ca(2+)-Dependent Inactivation

The neuronal L-type calcium channels (LTCCs) Ca(v)1.2α1 and Ca(v)1.3α1 are functionally distinct. Ca(v)1.3α1 activates at lower voltages and inactivates more slowly than Ca(v)1.2α1, making it suitable to support sustained L-type Ca(2+) inward currents (I(Ca,L)) and serve in pacemaker functions. We c...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Koschak, Alexandra, Reimer, Daniel, Walter, Doris, Hoda, Jean-Charles, Heinzle, Thomas, Grabner, Manfred, Striessnig, Jörg
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2003
Assuntos:
Cellular/Molecular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6740341/
https://ncbi.nlm.nih.gov/pubmed/12853422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-14-06041.2003
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