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Development and Validation of the Quantum Mechanical Bespoke Protein Force Field

[Image: see text] Molecular mechanics force field parameters for macromolecules, such as proteins, are traditionally fit to reproduce experimental properties of small molecules, and thus, they neglect system-specific polarization. In this paper, we introduce a complete protein force field that is de...

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Pubblicato in:ACS Omega
Autori principali: Allen, Alice E. A., Robertson, Michael J., Payne, Michael C., Cole, Daniel J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2019
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6740169/
https://ncbi.nlm.nih.gov/pubmed/31528808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.9b01769
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