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Breast Cancer Cells Transition from Mesenchymal to Amoeboid Migration in Tunable Three-Dimensional Silk–Collagen Hydrogels

Invading cancer cells adapt their migration phenotype in response to mechanical and biochemical cues from the extracellular matrix. For instance, mesenchymal migration is associated with strong cell-matrix adhesions and an elongated morphology, while amoeboid migration is associated with minimal cel...

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Detalhes bibliográficos
Publicado no:ACS Biomater Sci Eng
Main Authors: Khoo, Amanda S., Valentin, Thomas M., Leggett, Susan E., Bhaskar, Dhananjay, Bye, Elisa M., Benmelech, Shoham, Ip, Blanche C., Wong, Ian Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6739834/
https://ncbi.nlm.nih.gov/pubmed/31517039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsbiomaterials.9b00519
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