Safety and Tolerability of Initiating Maximum-Dose Sacubitril-Valsartan in Patients on Target Dose Renin-Angiotensin System Inhibitors

AIM: Sacubitril-valsartan has proven beneficial in heart failure with reduced ejection fraction. Guidelines recommend initiating half-dose sacubitril-valsartan before up-titration even to patients already on target dose angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers...

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Bibliographic Details
Published in:Cardiovasc Ther
Main Authors: Norberg, Helena, Bergdahl, Ellinor, Lindmark, Krister
Format: Artigo
Language:Inglês
Published: Hindawi 2019
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6739794/
https://ncbi.nlm.nih.gov/pubmed/31772613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/6745074
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