Chargement en cours...
Off-Pathway Assembly: A Broad-Spectrum Mechanism of Action for Drugs That Undermine Controlled HIV-1 Viral Capsid Formation
[Image: see text] The early and late stages of human immunodeficiency virus (HIV) replication are orchestrated by the capsid (CA) protein, which self-assembles into a conical protein shell during viral maturation. Small molecule drugs known as capsid inhibitors (CIs) impede the highly regulated acti...
Enregistré dans:
| Publié dans: | J Am Chem Soc |
|---|---|
| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Chemical
Society
2019
|
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6739737/ https://ncbi.nlm.nih.gov/pubmed/31244184 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b01413 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|